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doi 10.1111/dom.12824 98 DesaiAPetrovJHashashJGPatelHBrahmbhattBKochharGSet al

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Deficiency of Electron Transport Chain in Human Skeletal Muscle Mitochondria in Type 2 Diabetes Mellitus and Obesity

Mitochondrial transcription factor A (TFAM) is a nuclear gene-encoded mitochondrial transcription factor that binds upstream of the transcription start site and plays an important role in the replication, transcription, assembly, and maintenance of the stability of mtDNA (Kang et al., 2018

There are over 20 drugs in phase 2 and 3